Alterações hematológicas em cadelas portadoras de tumores de mama

Authors

  • Maria Anete Lallo Universidade Paulista
  • Tatiane Ferrarias
  • Adriane Stravino
  • Juliana Rodriguez
  • Roberto Zucare

Keywords:

dogs, hematology, mammary neoplasm

Abstract

In this study we describe the occurrence of hematological disorders in bitches with mammary neoplasm and analyze the possibility that alterations present can be used as a diagnostic parameter and prognosis. Two hundred and forty-six dogs with mammary neoplasms (123 with malignant and 123 with benign mammary tumor) and the same number of female dogs without mammary tumors were investigated for observation of hematologic abnormalities. The full blood test and measurement of proteins was carried out before any treatment for breast tumor. The diagnosis of mammary neoplasm was done by histopathology. Few animals with benign tumors had hematological disorders, but in malignant neoplasm the prevalence was 55%, and thrombocytosis, hyperproteinemia (hypergammaglobulinemia) and leucopenia (neutropenia) were the most prevalent abnormalities. Anemia and erythrocytosis had equilibrated occurrence (22 and 21%, respectively). Leukocytosis and thrombocytopenia were less hematologic changes observed. We concluded that because of the high prevalence of thrombocytosis, leukopenia and hyperproteinemia (hypergammaglobulinemia) in bitches bearing mammary tumors, the hematological abnormalities may be signaling of malignant neoplasm.

 

Downloads

Download data is not yet available.

Author Biography

Maria Anete Lallo, Universidade Paulista

Médica Veterinária pela Universidade Estadual de Londrina - UEL(1987), Especialização (1989) em Clínica e Cirurgia de Pequenos Animais pela Faculdade de Medicina Veterinária e Zootecnia da Universidade de São Paulo - USP, Mestre (1993) e Doutora (1998) em Epidemiologia Experimental Aplicada Às Zoonoses pela Universidade de São Paulo - USP. Professora titular da Universidade Paulista e da Universidade Cruzeiro do Sul. Experiência em Doenças Parasitárias e Clínica, com ênfase em zoonoses parasitárias oportunistas e emergentes. Professora e pesquisadora do Programa em Patologia Ambiental e Experimental da Universidade Paulista e dos grupos de pesquisa em Clínica e Doenças Infecciosas (UNIP) e Patologia Estrutural e Funcional Veterinária (UNICSUL)

Published

2016-09-26

Issue

Section

Clínica Médica e Cirúrgica