Terapêutica da ceratoconjuntivite seca canina: revisão bibliográfica

Canine keratoconjunctivitis sicca therapeutics: literature review

Autori

  • Lara Regina Pontes Cury Universidade de Brasília, Faculdade de Agronomia e Medicina Veterinária
  • Clarissa Machado de Carvalho Universidade de Brasília, Faculdade de Agronomia e Medicina Veterinária
  • Paula Diniz Galera Faculdade de Agronomia e Medicina Veterinária Universidade de Brasília http://orcid.org/0000-0002-6496-2538

Parole chiave:

dog, tear film, ophthalmology, dry eye, ocular surface

Abstract

Keratoconjunctivitis sicca (KCS) is a disease commonly seen in dogs that is characterized by the reduction or absence of lacrimal secretions. It can be classified as qualitative or quantitative, and both categories are able to elicit conjunctival and corneal inflammation, ocular pain, progressive corneal disease, and vision impairment. This disease’s treatment is based on reestablishing and maintaining ocular surface homeostasis. Patients may benefit from different therapeutic protocols, such as the use of lacrimomimetics, that increase lacrimal stability, helping to retain ocular humidity; lacrimostimulants, that promote lacrimal secretion; fatty acids, which play a role on meibum synthesis and block pro-inflammatory cytokine genic expression; blood products, based on promotion of epithelial growth factors; and stem cells, due to their self-renewing capabilities. Stable cases may benefit from the use of steroidal or non-steroidal anti-inflammatory agents on the control of clinical signs. Refractory cases may eventually benefit from surgical therapies, which include techniques for parotid duct transposition, gland transplants, and lacrimal puncta occlusion.

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Biografie autore

Lara Regina Pontes Cury , Universidade de Brasília, Faculdade de Agronomia e Medicina Veterinária

Graduada na FAV/UnB. Médica Veterinária Residente 2 do Programa de Residência em Clínica Cirúrgica de Pequenos Animais, FAV/UnB.

Clarissa Machado de Carvalho, Universidade de Brasília, Faculdade de Agronomia e Medicina Veterinária

Graduada em Medicina Veterinária, FAV/UnB.

Residência em Medicina de Animais Silvestres, FAV/UnB.

Mestre em Ciências Animais, com ênfase em Oftalmologia Veterinária, FAV/UnB.

Doutoranda do Programa de Ciências Animais, com ênfase em Oftalmologia Veterinária, FAV/UnB.

 

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Pubblicato

2023-10-10

Fascicolo

Sezione

Clínica Médica e Cirúrgica