Neutralization test in mice {MNT) using effective dose50 {ED 50) and lnternational Units {lU) on bovine's sera vaccinated with an inactivated rabies virus vaccine

Abstract

The results of neutralization test in mice (MNT) performed on bovine's sera that had been vaccinated previously with a commercialinactivated rabies vírus vaccine were calculated and expressed either in logarithm of Effective dose50 (ED 5J or in lnternationalUniVml (IU/ml). Statistical analysis revealed a Spearman nonparametric correlation of r= 0.6469, and when the use of IU/ml isimpeditive, the MNT titers expressed in ED 50 is still a useful procedure to determine if the bovines have responded to antirabies vaccination.